Neurocognitive Effects of Antiepileptic Drugs Frequently Used in Long Term Treatment of Epilepsies: A Review

نویسندگان

  • H. Jokeit
  • Béatrice Brunner
  • Ilan Oppenheim
  • Victoria Reed
چکیده

Antiepileptic drugs (AED) alter neuronal excitation levels and may result in neurocognitive changes. In recent years several new AEDs have been introduced which additionally are used to treat mood disorders, neuropathic pain, and migraine. Generally, very few controlled trials have systematically examined the neurocognitive side effects of AEDs. In particular, polytherapy with the newer AEDs is underinvestigated. In this paper we review the most relevant data on neurocognitive side effects of AEDs in current use in Switzerland for the long term treatment of epilepsies.

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تاریخ انتشار 2009